Neonatology : Neonatology Research

Neonatology Research

The clinical and research faculty of the Division of Neonatology/Department of Pediatrics of the University of Miami Miller School of Medicine are involved in a vast array of both basic research and clinical research activities. Over the past two decades, the neonatal program has been internationally recognized for its research reputation and expertise. The state of the art Batchelor Research Building provides the location for an active basic research laboratory, involved in addressing many problems requiring animal experimentation, including cardiovascular and respiratory response to infection and hypoxia in neonatal animal models as well as a developmental and molecular biology laboratory, active in investigating genetic influences in pulmonary hypertension and growth factors related to normal and deranged lung development. Clinical research has focused largely on neonatal cardiorespiratory physiology and pathology, including studies relating to the chronic lung process known as Bronchopulmonary Dysplasia. The following is a partial summary of the research currently being conducted:

  • Normal and abnormal lung development in models of lung injury
  • Inflammation and its influence on fetal and neonatal lung development
  • Chronic lung disease, pathogenic factors, prevention and outcome
  • Stem cell therapy for prevention/repair of lung injury in prematurity
  • Stem cells and pulmonary vascular remodeling
  • Early intervention program
  • Neurodevelopmental outcome after in-utero drug exposure
  • Pulmonary hypertension in neonates
  • Development of respiratory control mechanisms
  • Timing of PDA closure and major outcomes in premature infants
  • Advancement and new modes of neonatal respiratory support
  • The relationship of neonatal nutrition and immunity